Eligible respondents were invited to complete our consent protocol Rosser et al. Our goal was to assess the association between recent enema use and personal, behavioral, and environmental factors. Many women prefer something a bit more subtle, like a glance or eye contact and a smile. While both studies found similar results, suggesting that the association between enema use and HIV risk is reliable, the studies are old and were limited to a single question on enema use. Therefore, we used a block regression strategy. While water-based enemas have not been promoted, neither has the avoidance of enema use. While the biological risk of douching has been established through laboratory studies, very little has been published describing the rectal douching practices in sex between men. Also, there are communities online where people can find support, like enemata. Compliments that compliment are much more effective that ones that make her feel like a piece of meat and make you look creepy. Of the 6, eligible enrollees, 5, Most participants were young under 35 years , white non-Hispanic , well-educated with a college degree or higher , earned less than forty-thousand dollars, lived in an urban area and identified politically as either democrats or independents. All statistical tests were two-tailed, and all analyses were conducted in Stata 11 software StataCorp. To address this gap, as part of a larger trial, we conducted a behavioral epidemiologic investigation into the douching practices of MSM. We also examined if the two groups differed by behavioral and environmental factors. On all these measures, HIV-positive participants were significantly more likely to report engaging in douching than HIV-negative participants.